Additionally, the indole Main is substituted at R3 by using a carbonyl team which is also bonded into a napthalene moeity. Napthalene is often a bicyclic construction of two fused benzene rings. This carbonyl bridge of JWH-018 classifies it as being a ketone. JWH-018 is really an analog of THJ-018, by which the core indazole framework is substitute
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